Our lab studies the mechanism of eukaryotic chromosome replication. Chromosomes are the carriers of the genetic and epigenetic information and faithful chromosome replication is of fundamental ...

The replication of DNA is initiated at particular sites on the genome called replication origins (ROs). Understanding the constraints that regulate the distribution of ROs across different organisms ...

The research published in Nature on Dec. 25th, 2019, led by Dr. LI Guohong and Dr. ZHU Mingzhao from the Institute of Biophysics of the Chinese Academy of Sciences, has demonstrated that the histone ...

A research team led by scientists from the Helmholtz Institute for RNA-based Infection Research (HIRI) has introduced a new ...

Summary To successfully colonize their host, pathogens produce effectors that can interfere with host cellular processes. Here we investigated the function of CRN13 candidate effectors produced by ...

In mitosis, DNA replication is initiated through the actions of various multiprotein complexes that recognize the start sites within a chromosome and cause the separation of DNA into two ...

Researchers unveil append editing, a method that attaches chemical tags to DNA, expanding possibilities in medicine, agriculture, and biotechnology.

The genetic connections between DNA repair pathways and human cancer predisposition have fueled interest in the proteins that recognize and repair specific sites of DNA damage. The repair enzymes are ...

Researchers at the Smithsonian and around the world are working to sequence the genomes of every eukaryotic species on Earth in the next 10 years through the Earth BioGenome Project. Erin Malsbury ...